| abstract |
Provided is an aqueous oral preparation (a liquid preparation or a jelly preparation) of stable amlodipine. A desired aqueous oral preparation (a jelly preparation) of amlodipine which is stable and highly rapidly disintegrable could be produced by using an anionic surfactant having a sulfate group or a sulfonate group as a stabilizing agent for amlodipine in an aqueous solution, preparing a liquid preparation which is stable in a pH range of from 5 to 7 as a liquid property, and also adding and mixing a gellant, a fine powdery solid and a gelation adjusting agent. As a result, it became possible to provide a novel oral preparation (a liquid preparation or a jelly preparation) which is easily taken by an elderly subject having decreased function of swallowing and difficulty in taking a tablet. |