| abstract |
(57) [Problem] To provide a pharmaceutical composition having excellent storage stability. SOLUTION: The general formula: (Wherein, R 1 is an optionally substituted C 1 -C 4 alkyl group, Amino group, cyano group; R 2 ; optionally substituted C 1 -C 4 Phenyl group having a substituent; an alkyl group, a substituted C 3 -C 4 alkenyl group, 4-6-membered cyclic amino group which is substituted; R 3 R 4: optionally substituted C 1 -C 4 alkoxycarbonyl Group, 1,3,2-phospholinan-2-yl group, A calcium blocker having a 5,5-dimethyl-1,3,2-phosphorinan-2-yl group; R 5 : a C 1 -C 4 alkyl group) or a pharmaceutically acceptable salt thereof, and an aqueous solution of a pharmaceutical composition or A calcium blocker-containing drug composition containing a pharmacologically acceptable alkaline medium capable of imparting at least pH 8 to the dispersion. |