| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ab84e0b014de5fd7b550d62211c93af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d067760eb18f571f4408cdce6c9236c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a5e754e82c91ed047afe48e5f610c97
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8c8ecea126b94a601d697e443ea69a0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0013 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01H1-00 |
| filingDate |
2009-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25cb31aee574502009a3f68a448fd31c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d34a5d5c9d43466aa33239cb024e09a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3c4ddeaa39ffa340d23fa323751b7cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49c8a023570680e82bc52eeb80b2ee90 |
| publicationDate |
2010-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010062787-A1 |
| titleOfInvention |
Bioluminescence imaging of myeloperoxidase activity in vivo, methods, compositions and apparatuses therefor |
| abstract |
Methods of imaging distribution of myeloperoxidase activity in a subject are disclosed. These methods include the use of bioluminescent substrates, including luminol and wavelength-shifted analogues of luminol. Bioluminescent myeloperoxidase substrates that emit light at longer wavelengths compared to luminol are shown to be useful for imaging myeloperoxidase activity in vivo. The disclosed methods can be used for imaging sites of inflammation and other pathological conditions associated with abnormal levels of MPO activity in vivo. Methods of synthesis of luminol analogues are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10092565-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2697726-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9464079-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012127441-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3673923-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014517913-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012142392-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9446151-B2 |
| priorityDate |
2008-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |