| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7115ef17a0cce55f36229865e31ea6a0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5094
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
1999-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a2e945ee6b8b3f71103d7b2c3f5d967
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10ac6b7acf990633a9bed8461f3b58c0 |
| publicationDate |
2000-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6022699-A |
| titleOfInvention |
Myeloperoxidase assay of endotoxin-induced inflammation |
| abstract |
An improved model of endotoxin-induced inflammation is obtained by eliminating the interference in the biochemical assay of myeloperoxidase caused by endogenous reductants and cellular constituents containing free thiol functional groups. The interference was eliminated by 1) extensively diluting soluble, interfering substances and 2) blocking tissue sulfhydril functional groups during tissue homogenization. The improved model can be used to assess the therapeutic potential of anti-inflammatory agents. For example, the model can be used to evaluate topically administrable ophthalmic anti-inflammatory agents in Lewis rats. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011021640-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011133581-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006020762-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006035308-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8652442-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007154977-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7195891-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010062787-A1 |
| priorityDate |
1999-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |