| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4260a256b5f28ea7d92b4c1f5b921d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04e1c474d5d1337c44f540fee92191ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97317c95087095cfd69cd1c948ae9ba5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c94f84a357c1ca9efe3aefd5985b92c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-51 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 |
| filingDate |
2009-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18deb6785006b2593c491279834849e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a59bb13610a20c1171123e17ca0a5367
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3813b75b70a318b6659a6ca34e5b132 |
| publicationDate |
2010-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2010029303-A1 |
| titleOfInvention |
Gene silencing |
| abstract |
The invention provides a mirtron or a gene capable of expressing a mirtron for use in modifying the expression of a target gene in a mammalian cell to prevent or treat a disease, the sequence of the mirtron comprising: (i) a 5' splice site; (ii) a 3' splice site; (iii) a branch-point recognition sequence; (iv) a 3' polypyrimidine tract greater than 15 nucleotides in length; and (v) an antisense sequence that is at least partially complementary to a sequence in the target gene. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112805382-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020003006-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11332760-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013063487-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10590420-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014082644-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103890179-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3661523-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016016449-A1 |
| priorityDate |
2008-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |