| abstract |
Provided are thioxo isoindoline compounds, and pharmaceutically acceptable salts, solvates, and stereoisomers, thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed. A compound of formula (I) or a pharmaceutically acceptable salt, solvate or stereoisomer thereof, wherein one of R 1 -R 4 is NH 2 or NO 2 , and the others of R 1 -R 4 are each hydrogen; R 5 and R 6 are each independently thioxo or hydrogen, provided that at least one of R 5 or R 6 is thioxo; and R 7 and R 8 are each indepently thioxo or oxo. |