Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_488ab6a2c22239841681b2b8183b901b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e23a4c9cd982ccdb6082585045b94b7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3aeb5e606c1fb1a2ff49eb8ab418b01a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_80e7573d60d56d2d64d48cfdcd3b8052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28627059e1e1bdd2890ef9b952b82b8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ea1c3f4caa3a87ce001a5d996df62b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f0666ada7b158089d3a4fa378fb0aa0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e559743173473475142b7bd8a978298 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e72d950c05a0d97afa569ed9f14dd91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24430c627c7e011dc7560cb085ee51b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ff4b03842b0118998a09c79e617caa2 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 |
filingDate |
2009-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8aee5883da32fcaa2da0de83593d191a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a408c7a58fa9ab3efaf2a5b8a6a33463 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98f4b36beb35b5120205ecf380043f90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e3537d5aefd2291b465ab329ff92112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddc74331910adf30b53071a868dc7056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e705de6e3ca77e007769aa77e6ec57dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85c2ec67c19c927346d2738df41d96a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cca66e4a2369becca606ac71fff42857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5163618a283a5fb601c2f1d6ccd2610 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1c1b5c5987f540073550225eaf0acf1 |
publicationDate |
2009-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2009134086-A2 |
titleOfInvention |
Pharmaceutical formulation for treatment of cardiovascular disease |
abstract |
The present invention provides (1) a release-controlled pharmaceutical formulation including a Simvastatin-containing early release compartment and a Losartan-containing retarded release compartment, (2) a release-controlled pharmaceutical formulation including a Simvastatin-containing early release compartment and an Olmesartan-containing retarded release compartment, (3) a release-controlled pharmaceutical formulation including a Simvastatin-containing early release compartment and a Valsartan-containing retarded release compartment, (4) a release-controlled pharmaceutical formulation including a Simvastatin-containing early release compartment and a Candesartan-containing retarded release compartment, (5) a release-controlled pharmaceutical formulation including a Rosuvastatin-containing early release compartment and a Losartan-containing retarded release compartment, (6) a release-controlled pharmaceutical formulation including a Rosuvastatin-containing early release compartment and an Iresartan-containing retarded release compartment, and (7) a release-controlled pharmaceutical formulation including a Rosuvastatin-containing early release compartment and a Candesartan-containing retarded release compartment. The pharmaceutical formulation of the present invention minimizes an antagonism between drugs and side effects of the drugs and maximizes unique effects of drugs because different drugs contained in different compartments in the formulation are released with a time difference. The pharmaceutical formulation of the present invention prepared by the specific combination of two drugs exhibits remarkably excellent effects of treatment or prevention of disease as compared with a single medication or a simply combined medication. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102304910-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103002883-A |
priorityDate |
2008-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |