| abstract |
The present invention relates to a composite pellet comprising aspirin, a hypoglycemic agent and an HMG-CoA reductase inhibitor, and specifically a composite having an enteric coating on the outside of the main layer containing aspirin and an outer coating with an HMG-CoA reductase and a hypoglycemic agent. It is about pellets. The composite pellet according to the present invention comprises a main layer coated with 25 to 35% by weight of aspirin in 40 to 55% by weight of inert sugar particles; Enteric base layer coated with 10 to 15% by weight of the enteric base on the outside of the main layer; and 0.2 to 2.5% by weight of sulfonylurea-based hypoglycemic agent and 2.5 to 15% by weight of HMG-CoA reduction on the outside of the enteric base layer Including an outer layer coated with an enzyme inhibitor, wherein the hypoglycemic agent is one drug selected from the group consisting of glibenclamide and glimepiride among sulfonyl urea drugs, HMG-CoA The reductase inhibitor is characterized in that it is one drug selected from the group consisting of simvastatin, atorvastatin calcium and roschvastatin calcium.n n n n Pellets, aspirin, hypoglycemic agents, HMG-CoA reductase inhibitors |