abstract |
Provided is a compound represented by formula (I) having a PAI-1 inhibiting action. [In formula (I), R1 represents an optionally substituted C6-10 aryl group etc., T represents a single bond etc., m is 0 or 1, when m is 0 G represents -N-C(=O)-CO2H etc., when m is 1 G represents an oxygen atom etc., R2 represents an optionally substituted C6-10 aryl group etc, E represents formula (II) (wherein one of R31, R32, R33 and R34 represents R1-T- and the remaining three each individually represent a hydrogen atom etc., and R35 is -X-Y', a hydrogen atom etc.), X represents -CH2- etc., Y' represents a carboxyl group etc. and M represents a single bond etc.] |