http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009098313-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a3e06b739fa9ae6a96b7ba808b9cd0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_589b4e7af26cc1f1fd30dee3d5cb9ced http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4d2df2ef437e6063397c55b825ef0bf |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-974 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-86 |
| filingDate | 2009-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ce6bd9055b831dc8666c99940d53b15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0074081870687dabd6f897f825324d39 |
| publicationDate | 2009-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2009098313-A1 |
| titleOfInvention | Time-course measurement of enzymatic activity corrected for impacts of disturbances relating to the reaction of the enzyme with a substrate |
| abstract | The invention relates to time-course measurement of enzymatic activity corrected for impacts of disturbances relating to the reaction of the enzyme with a substrate. The in vitro method of the invention is especially intended for the measurement of clotting or the fibrinolysis activity in vitro. The invention enables to measure the exact time course of an enzymatic activity that develops and/or disappears in a reaction mixture, especially in a blood sample. The invention thus relates to a method of determination of the course of an enzyme activity that is variable in time, wherein said activity is probed by conversion of a substrate of the enzyme, comprising, in a selected test set up and for a determined substrate of the enzyme, the determination of the velocity of signal production (dFdiag/dt) resulting from a time curve of the signal (Fdiag=f(A)) obtained from splitting said substrate when it is contacted with a determined initially fixed concentration of the enzyme (E) and providing a 'diagnostic plot' with the values of (dFdiag/dt) against the signal (Fdiag) and determining whether said diagnostic plot is either a straight line or a parabola and in the same test conditions, for a given test sample, the determination of the signal production (Fexp) resulting from splitting the substrate by the enzyme generating in and/or disappearing from the sample and providing the time curve of signal Fexp=f(t); and transforming the obtained experimental value of the signal (Fexp) into an ideal value (Ftransf). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9428790-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018151602-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9938563-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-028341-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013190071-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2677037-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3363912-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013015717-A3 |
| priorityDate | 2008-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 161.