abstract |
Methods and materials are provided for selecting and/or treating a subject based on a Fc?RIIA morphism, or a Fc?RIIB polymorphism, or both an Fc?RIIA polymorphism and a Fc?RIIB polymorphism, for treatment with a therapy including an antibody therapy such as rituximab. Methods are also provided for designing, making, screening, testing and/or administering antibodies as well as for optimizing antibody therapies based upon a subject's Fc?RIIA polymorphism, or Fc?RIIB polymorphism, or both the Fc?RIIA polymorphism and the Fc?RIIB polymorphism. |