| abstract |
Disclosed are a novel pyrazole derivative and an androgen receptor antagonist containing the pyrazole derivative. Specifically disclosed is a compound represented by the formula (I') below or a salt thereof. (In the formula, R1 represents a hydrogen atom, a group having a carbon atom serving as a bonding hand, a group having a nitrogen atom serving as a bonding hand, a group having an oxygen atom serving as a bonding hand or a group having a sulfur atom serving as a bonding hand; R2 represents a phenyl group having a cyano (which may further have a substituent other than cyano); R3 represents a hydrogen atom, a group having a carbon atom serving as a bonding hand, a group having a nitrogen atom serving as a bonding hand, a group having an oxygen atom serving as a bonding hand or a group having a sulfur atom serving as a bonding hand; R4 represents an optionally substituted cyclic group; and X represents an optionally substituted methylene or CO.) |