| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_566ecfbd59edb629abe74cfb002e0bc6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fdf7bd6febbca102c9379d57f1934ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5305109c4efec4cbcdd8bc05bdb00399 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C225-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-80 |
| filingDate |
2008-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ced884905a9c0d62c774e2d37dfd1c4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e523311012ad28f630eee034090bc741 |
| publicationDate |
2008-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2008098527-A1 |
| titleOfInvention |
Method for the preparation of 5-benzyloxy-2-(4-benzyloxphenyl)-3-methyl-1h-indole |
| abstract |
A method for the preparation of 5-benzyloxy-2-(4-benzyloxyphenyl)-3-methyl-1H-indole of formula (1) by reaction of 2-bromo-4'-benzyloxypropiophenone and 4-benzyloxyaniline hydrochloride, in which high purity of the product is achieved by isolation of the intermediate, N-(4-benzyloxyphenyl)-α-amino-4-benzyloxypropiophenone of formula (10), in the solid state. The method may be used for the preparation of bazedoxifen of formula (2). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104098499-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IT-201800006562-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7968732-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104098499-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2426105-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8431739-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7353617-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10844047-B2 |
| priorityDate |
2007-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |