http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104098499-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10c3f12979e7751f6e54ae5594988766 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fcaa03b795cd8da869d58e8f28bf52e5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-12 |
| filingDate | 2013-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2e6146bfcfe79aa8e33409dbbbbf7f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_699232252e1dfd1a5f52aa8f9d5b398e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f8b0ec4d305b9fdef05a46154a4bbba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1093800ce8ca6411fd6688c9d4b8603 |
| publicationDate | 2014-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104098499-A |
| titleOfInvention | The preparation method of 5-benzyloxy-2-(4-benzyloxyphenyl)-3-methyl-1H-indole |
| abstract | The invention discloses a preparation method of 5-benzyloxy-2-(4-benzyloxyphenyl)-3-methyl-1H-indole. The preparation method comprises the following steps: (1) in an alcoholic solvent, under the action of a base, carry out condensation reaction of compound II and compound III; (2) mix the reaction liquid of step (1) with protonic acid, and carry out Bischler -Mohlau indole ring closure reaction, then. Compared with the prior art, the synthesis route of the present invention combines the first-step condensation reaction and the second-step Bischler-Mohlau indole ring-closing reaction into a "one-pot" reaction, which is easy to operate; the reaction product I is directly separated out from the reaction solvent , which greatly simplifies the post-reaction treatment process, has high purity and high reaction yield, and is suitable for scale-up production. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10844047-B2 |
| priorityDate | 2013-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.