| abstract |
PPARϜ agonists containing tricyclic compounds represented by the general formula (I) or pharmaceutically acceptable salts thereof as the active ingredient, wherein R1 is optionally substituted lower alkyl or the like; R2 and R3 may be the same or different and are each optionally substituted lower alkyl or the like; R4 and R5 may be the same or different and are each hydrogen or the like; Q1-Q2-Q3 is CH=CH-CH=CH or the like; Y is a single bond or the like; Z1-Z2 is C=CR13 or the like wherein R13 is hydrogen or the like; and A is -COOH or the like. |