| abstract |
The present invention provides compositions and methods for diminishing signs of photodamage and/or aging. Certain of the methods comprise contacting skin with an effective amount of one or more elastase enzymes. Certain of the compositions reduce the evidence of elastotic material when contacted with skin. The compositions and methods provide for topical application as well as administration by injection Certain of the compositions comprise an elastase, e.g., an at least partially purified bacterial elastase. Certain of the methods comprise removing at least a portion of the epidermis or stratum corneum prior to contacting the skin with the composition comprising an elastase. |