| abstract |
The present application relates to compounds of the formula (I) which act as stimulators of soluble guanylate cyclase and to their use for treatment and/or prevention of heart failure, angina pectoris, hypertension, pulmonary hypertension, ischaemias, vascular disorders, thromboembolic disorders and arteriosclerosis. L-CH<SUB>2</SUB>-M-Q (I) in which L is phenyl, pyridyl, furyl, thienyl, thiazolyl, oxazolyl, isothiazolyl, isoxazolyl or (C<SUB>5</SUB>-C<SUB>7</SUB>)-cycloalkyl, M is a bicyclic heteroaryl group of the formula (a-1), (b-1) or (c-1), in which the attachment site to the group is -CH<SUB>2</SUB>-L, the attachment site to the group is Q, and A, B, D and E are each CH, CR<SUP>1</SUP> or N, where not more than two of the ring members A, B, D and E are the same, and Q is an unsaturated or aromatic 5- or 6-membered heterocycle having up to four heteroatoms from the group of N, O and/or S. |