http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008026922-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7279fac5c2d42290290a4774d8abec85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_846ddf85cddd12c15d7a455c01f36c00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5de66fcc7c37934b48c684ca26e9cc0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2007-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94047c53aab4a066ab86189562331854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f46607f1d6f26ade92fbdf4587aef552 |
| publicationDate | 2008-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2008026922-A1 |
| titleOfInvention | A pharmacogenetic method for prediction of the efficacy of methotrexate monotherapy in recent-onset arthritis |
| abstract | Pharmacogenetic methods for determining a predicting responsiveness to antifolate therapy for subjects that present with recent-onset undifferentiated arthritis. The methods are based on the determination of a set of clinical parameter values and determining a predicted responsiveness to antifolate therapy by correlating the parameter values with predefined responsiveness values associated with ranges of parameter values. Parameters values that are decisive for responsiveness to antifolate therapy may include polymorphisms in the methylenetetrahydrofolate dehydrogenase (MTHFD1) gene as well as in three genes involved in the adenosine release pathway, the presence or absence of Rheumatoid factors, gender, pre- or postmenopausal status and/or smoking status. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2542699-A1 |
| priorityDate | 2006-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.