| abstract |
Methods for modulating apoptosis and neurite outgrowth in cells by modulating levels of PtdIns(4,5)P<SUB>2</SUB>. Agents for such modulation, including agents which inhibit or activate type I and type II PIP kinases, and methods for identifying such agents. Methods for treating or preventing hyperproliferative disorders and neurodegenerative diseases using such agents. |