abstract |
Antisense compounds, compositions and methods are provided for modulating the expression of phosphatidylinositol-4- phosphate 5-kinase, Ia. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding phosphatidylinositol-4-phosphate 5-kinase, Ia. Methods of using these compounds for modulation of phosphatidylinositol-4-phosphate 5-kinase, Ia expression and for treatment of diseases associated with expression of phosphatidylinositol-4-phosphate 5-kinase, Iα are provided. |