| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5164a19624acf1df7770990b7d1413fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f09c7c663de4f9fa65cad3b5970cc951 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2006-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da2b49858da581bfb9dff341cba1c996
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce9be82c50e7733be272e2e30b73b9fd |
| publicationDate |
2007-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007076420-A2 |
| titleOfInvention |
Apparatus, methods and products for detecting genetic mutation |
| abstract |
Methods for detecting genetic mutation allowing detection of very low frequency mutation. Methods comprise treating RNA: DNA heteroduplexes of interest with ribonuclease treatment coupled with DNA polymerase treatment. RNA:DNA heteroduplexes of interest are preferentially targeted for digestion by ribonuclease and subsequent sequence extension by DNA polymerase. Methods may be carried out partially or entirely manually, automatically, and combinations thereof. Methods may be performed wholly or partially in solution, on solid phase media, in large scale, adapted for high throughput analysis, and any combinations thereof. Apparatus and products for detecting genetic mutation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016037358-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10023906-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009543582-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10995367-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9890375-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10544451-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4909413-B2 |
| priorityDate |
2005-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |