| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7835671b80b79aab7dbfacf5977bd2d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_829870c3d1719dc25f6939097d79a0e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e08cbdf60ad1d57744ac8cb0197e8a95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff12915e4d1ce5442d479bd5a88d2e70 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2005-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab1e5f3bd7b18a55f88c2a59f3f50df1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b53397c259255c3924abe412d501e367
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f2520d1c430ab4a6522d2f2b1d0735e |
| publicationDate |
2007-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2007037676-A1 |
| titleOfInvention |
Method and means for targeted nucleotide exchange |
| abstract |
The invention pertains to a method for targeted alteration of a duplex acceptor DNA sequence, comprising combining the duplex acceptor DNA sequence with a donor oligonucleotide, wherein the duplex acceptor DNA sequence contains a first DNA sequence and a second DNA sequence which is the complement of the first DNA sequence and wherein the donor oligonucleotide comprises a domain that comprises at least one mismatch with respect to the duplex acceptor DNA sequence to be altered, preferably with respect to the first DNA sequence, and wherein a section of the donor oligonucleotide is methylated to a higher degree than the second DNA sequence and/or wherein the second DNA is methylated to a lower degree than the corresponding section of the donor oligonucleotide, optionally in the presence of proteins that are capable of targeted nucleotide exchange and to oligonucleotides for use in the method. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011258711-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11008579-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2562261-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9365860-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009082190-A1 |
| priorityDate |
2005-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |