Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_29e2c5b632bd1c55cf0ad55f18102375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d546bc6ca75222d69a3941051be3b8ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac942009f7249031de3341adfc60299d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e81f14b142d1611b6819305eeac98cc8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa43f626b51f8c3ebc3403e0a92749ca |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-12 |
filingDate |
2006-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9be4b783cccabcf175d075eda0192aa8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bad0caefe08bc4cfd4156600a85def6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_072f9735edf051f544d9990b2d9ff487 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15e0ce7b6e9116e1ff6f4d1d93835c4a |
publicationDate |
2007-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2007024113-A1 |
titleOfInvention |
Process for the preparation of chiral 3-hydroxy pyrrolidine compound and derivatives thereof having high optical purity |
abstract |
The present invention relates to an effective process for the preparation of optically pure chiral 3-hydroxypyrrolidine or derivatives thereof. More particularly, the present invention relates to an efficient process for the preparation of chiral 3-hydroxypyrrolidine or derivatives thereof, comprised of introducing a suitable protecting group to the starting material 4-chloro-3-hydroxybutyronitrile. Introduction of the hydroxy-protecting group provides advantages: efficient prevention of formation of side products, enhanced performance of the reduction of the nitrile group of the starting material, and enhanced performance of in-situ inĀ¬ tramolecular cyclization. The chiral 3-hydroxypyrrolidine compound is produced in high yield and with high purity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111518015-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010058429-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8445700-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111763228-A |
priorityDate |
2005-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |