Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_870832d1e91e735015b1f7a4395b6084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f3109befbff2bcd31b2339d5610e0ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4e69a456f4fcac792f8f7d7b967b4b2 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2005-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3089931cc34578daf2f221a9980cdd97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c47499b5f34840e7f39b2c83ff8c22ae |
publicationDate |
2005-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005108999-A2 |
titleOfInvention |
Diagnostic and therapeutic use of kcnj6 for alzheimer’s disease |
abstract |
The present invention discloses a dysregulation of the KCNJ6 gene and the protein products thereof in Alzheimer's disease patients. Based on this finding, the invention provides a method for diagnosing and prognosticating Alzheimer's disease in a subject, and for determining whether a subject is at increased risk of developing Alzheimer's disease. Furthermore, this invention provides therapeutic and prophylactic methods for treating and preventing Alzheimer's disease and related neurodegenerative disorders using the KCNJ6 gene and its corresponding gene products. Screening methods for modulating agents of neurodegenerative diseases are also disclosed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3892738-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021204407-A1 |
priorityDate |
2004-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |