Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2416209a829dab4f113fab8c911e1cba http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb72d3ecf237a13b826e3b8778e6304c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4ef6af2df37757c2136963317e10563 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_534dddca7cff1e1107dc5048981bf1e9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 |
filingDate |
2005-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_381bf8683f338dd1c3c31662293d69c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bb66c4738f28cc1126aca66511d9276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_714b708e6f050dd13f93975f2dc79283 |
publicationDate |
2005-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2005103693-A2 |
titleOfInvention |
Methods, compositions and compound assays for inhibiting amyloid-beta protein production |
abstract |
A method for identifying compounds that inhibit amyloid-beta precursor protein processing in cells, comprising contacting a test compound with a vasopressin receptor polypeptide, or fragment thereof, and measuring a compound-polypeptide property related to the production of amyloid-beta peptide. Cellular assays of the method measure indicators including second messenger and/or amyloid beta peptide levels. Therapeutic methods, and pharmaceutical compositions including effective amyloid-beta precursor processing-inhibiting amounts of vasopressin receptor expression inhibitors, are useful for treating conditions involving cognitive impairment such as Alzheimers Disease. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015009988-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2579745-C2 |
priorityDate |
2004-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |