abstract |
The invention provides a human AVPR2 which is associated with the hematologicalndiseases, cardiovascular diseases, disorders of the peripheral and central nervousnsystem, genitourinary diseases, respiratory diseases, metabolic diseases and cancer.nThe invention also provides assays for the identification of compounds useful in thentreatment or prevention of hematological diseases, cardiovascular diseases, disordersnof the peripheral and central nervous system, genitourinary diseases, respiratoryndiseases, metabolic diseases and cancer. The invention also features compoundsnwhich bind to and/or activate or inhibit the activity of AVPR2 as well as pharmaceuticalncompositions comprising such compounds. |