| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fc19d8d6ba9ad5c1fa5770341472b56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bca582ed840b7a677d02fb63aebc5ade |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
2004-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8baa2e497bece6348c41b00eb2f22e8e |
| publicationDate |
2005-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005012912-A2 |
| titleOfInvention |
Lamp-1 membrane expression by cancer cells |
| abstract |
The invention provides methods of detecting a cancer cell and methods of reducing the proliferation of a cancer cell. For reducing the proliferation, the method consists of contacting the neoplastic cell with a cytotoxic or cytostatic binding agent specifically reactive with LAMP 1, a lysosome-associated membrane protein expressed on the cancer cell membrane. A method of reducing tumor growth through the targeting of a cytotoxic agent using an antibody specific for LAMP-1 is also provided, as is a method of detecting cancer cells expressing LAMP-1, to aid in diagnosis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016504342-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105007941-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2013369339-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105007941-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014102299-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9809653-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3400961-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023034571-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014102299-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7611703-B1 |
| priorityDate |
2003-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |