| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9a652d3fb63e6921579775d6eb0a3fa |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1027 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate |
2003-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a5e334b9da8e1cfc99bc18e6e5ad617
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53adaad0bf1f3ff623cfc1282e469a13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_597390737d751fb7d06d8f4c408e3960
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f047b27dfd01703d0703f68eef640364
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ccbb530e89b5117d166bcbb7f2280af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c21a2c71dc203307c3055e27048621e |
| publicationDate |
2005-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2005010212-A1 |
| titleOfInvention |
Polynucleotide sequence variants |
| abstract |
We describe here an in vitro method of redistributing sequence variations between non-identical polynucleotide sequences, by making a heteroduplex polynucleotide from two non-identical polynucleotides; introducing a nick in one strand at or near a base pair mismatch site; remvoing mismatched base(s) from the mismatch site where the nick occurred; and using the opposite strand as template to replace the removed base(s) with bases that complement base(s) in the first strand. By this method, information is transferred from one strand to the other at sites of mismatch. |
| priorityDate |
2002-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |