http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005003743-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_626e03ba322f238340e0bc64ce46b36c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c8cbbf2290b3f3a9988da29598baa2c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-76 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-648 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54373 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-4788 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-76 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-55 |
| filingDate | 2004-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f5e1efe51974028e0d1b53b7a2969ec |
| publicationDate | 2005-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2005003743-A2 |
| titleOfInvention | Apparatus and methods for surface plasmon-coupled directional emission |
| abstract | Methods and apparatus for fluorescence detection which can increase sensitivity by as much as 20 to 1000-fold are described. This method can preferably also decrease the contribution of sample autofluorescence to the detected signal. The method uses coupling of excited fluorophores with the surface plasmon resonance present in thin conductive films, for example silver, gold, aluminum, copper, or the like. The phenomenon of surface plasmon-coupled emission (SPCE) occurs for fluorophores in a volume adjacent to the conductive layer. This interaction is independent of the mode of excitation, that is, does not require evanescent wave or surface-plasmon excitation. However, such modes of excitation can be advantageous. SPCE can occur over a narrow angular distribution, converting normally isotropic emission into easily collected directional emission. In preferred embodiments, up to 50% of the emission from unoriented samples can be collected, usually much more than typical fluorescence collection efficiencies, which can be 1% or less. Examples are presented showing how simple optical configurations can be used in diagnostics, sensing, or biotechnology applications. Surface plasmon-coupled emission is likely to find widespread applications throughout the biosciences. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8877129-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2112500-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2060904-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102007033124-B4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2431234-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7709808-B2 |
| priorityDate | 2003-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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