| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_55d564ca76bdac23a1a73565eb1e0ef7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f7e75e8b1c5d9bdc1b845a934eba308
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1aafa95bdc031e963c7a2fe9d823e51e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-34 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-34 |
| filingDate |
2004-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06ef6660a5e52fc09e0601edbf6b7fb2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f7837421bc81f619f10cc0915192ace |
| publicationDate |
2004-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2004103315-A2 |
| titleOfInvention |
Treatment of ophthalmic infections using antimicrobial peptides |
| abstract |
The present invention discloses a use by administering to a vertebrate inflicted with the ophthalmic infection a therapeutically effective amount of an antimicrobial peptide which is derived from alpha-melanocyte-stimulating hormone (a-MSH) and biologically functional equivalents thereof. Specifically, the antimicrobial peptides derived from alpha-melanocyte-stimulating hormone (a-MSH) include a-MSH (1-13) which is SYSMEHFRWGKPV (SEQ ID NO: 4), a-MSH (4-10) which is MEHFRWG (SEQ ID NO: 2), a-MSH (6-13) which is HFRWGKPV (SEQ ID NO: 3), a-MSH (11-13) which is KPV (SEQ ID NO: 1), and a KPV dimer (SEQ ID NO: 5). The ophthalmic infection can be caused by a microorganism which include a bacteria, a fungi or a virus. The vertebrate includes a bird and a mammal. The antimicrobial peptide has anti-bacterial, antifungal, and antiviral properties and therefore can be administered at the onset of the ophthalmic infection before the microorganism causing the infection is determined as well as thereafter. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008142517-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008142517-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1667703-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1667703-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102741272-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102659926-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012126172-A1 |
| priorityDate |
2003-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |