http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004053460-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d55dd4da0d8f5bfa72abe0507617311d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-532 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N- |
| filingDate | 2003-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a8c711b8cf4fec83019185da37e0f44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23176e7c81044fcffa82f28f06337f5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0e6d65cc83b0dd5d8db971a2eb16f4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b813b65004940ec9f027fb8e45820e26 |
| publicationDate | 2004-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2004053460-A2 |
| titleOfInvention | Carrier-ligand fusions and uses thereof |
| abstract | Improved methods for purification, detection or characterization of molecules have been described in embodiments of the present invention. The improved methods rely on the ability to create a carrier reagent which is capable of (i) binding to a matrix either specifically or non-specifically; and (ii) forming a covalent linkage with any ligand having a nucleophilic group or a thioester as a result of a simple reaction which does not require a variety of chemical reagents or sophisticated chemistry. The covalent linkage between the carrier and the ligand relies on the chemical reaction between a thioester and a nucleophilic group. The carrier should either contain a reactive thioester which if it is a protein should be at the C-terminal end of the protein or a reactive nucleophilic group which if it is a protein should be at the N-terminal end and should preferably be a cysteine or selenocysteine. The ligand requires a reactive nucleophilic group to react with the thioester on the carrier or if the carrier has a reactive nucleophilic group, the ligand should have a reactive thioester. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7517671-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8119390-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020129027-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8486660-B2 |
| priorityDate | 2002-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 367.