| abstract |
An anti-inflammatory agent which contains as an active ingredient either a 4-aminotetrahydroquinoline derivative represented by the formula (I): (I) (wherein R1 represents hydrogen, (un)substituted lower alkyl, (un)substituted aryl, etc.; R2 and R3 are the same or different and each represents hydrogen, (un)substituted lower alkyl, etc.; R4 and R5 are the same or different and each represents hydrogen, etc.; R6 represents hydrogen, etc.; R7 represents (un)substituted cycloalkyl, (un)substituted aryl, etc.; R8 represents (un)substituted lower alkyl, (un)substituted aryl, etc.; and R9, R10, R11, and R12 are the same or different and each represents hydrogen, halogeno, (un)substituted lower alkyl, etc.) or a pharmacologically acceptable salt of the derivative. |