| abstract |
A compound represented by the following formula (I); a pharmaceutically acceptable salt of the compound; and a solvate thereof. [In the formula (I), X represents CH or N; Z represents -O-, -NH-, or -C(=O)-; R and R' each represents hydrogen, hydroxy, halogeno, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkoxy, amino, aminocarbonyl, or an optionally substituted heterocyclic group; and A represents an optionally substituted specific carbocyclic or heterocyclic group.] The compounds have excellent TGFß inhibitory activity. |