abstract |
This invention provides compounds defined by Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, Q, Y6 Y8, R2, R4, and R7 are as defined in the specification. The invention also provides pharmaceutical compositions comprising a compound of Formula (I) and the use of the compounds of Formula (I) for manufactures of medicaments useful for the treatment of rheumatoid arthritis (MMP-13 inhibitors). |