abstract |
Disclosed is an amide-containing heterobicyclic metalloprotease inhibitory compound having a heterobicyclic matrix metalloproteinase (MMP) -13 inhibitory activity. A compound represented by the following formula (1): And N-oxides, pharmaceutically acceptable salts, prodrugs, formulations, polymorphs, racemic mixtures and stereoisomers of the compounds. [Selection figure] None |