| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1b4b3b62726ac1c72f80be05f5ccdbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed50f857f3303d76f0b34d79a3200258
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b42394c3d9a7d73d058179a790b0d177 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6901
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y114-16001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2003-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e78ba8446212b883e8d51879281eed3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82247beead74f134a97cea7d8725d622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b843c22a340eeb6df32967afd23b69f |
| publicationDate |
2003-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03087383-A1 |
| titleOfInvention |
Compositions for delivering enyzmes involved in amino acid metabolism using recombinant ademo-associated virus virons (raav virons), and method and use for treating aminoi acid metabolic disorders using such raav virons |
| abstract |
Methods for delivering a heterologous gene to a mammalian subject using recombinant adeno-associated virus (rAAV) virions are described. Recombinant AAV virions containing a heterologous gene encoding a metabolic protein are delivered to a mammalian subject having a metabolic disorder. The rAAV virion-delivered heterologous gene is expressed at a therapeutic level thereby ameliorating a sign or symptom of the metabolic disease. Exemplary examples of metabolic diseases are those caused by defects in aromatic amino acid metabolism. Exemplary examples of heterologous genes include those encoding an aromatic amino acid hydroxylase, aromatic amino acid decarboxylase, and enzymes involved in tetrahydrobiopterin synthesis. Methods for treating phenylketonuria are also described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11697825-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11027000-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11512327-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2788484-C2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11497576-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11193129-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11752181-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11542506-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11584780-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10335466-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11759506-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10577627-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10584337-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10610606-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11198873-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10570395-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10983110-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10920227-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10597660-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11603542-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11739345-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11298041-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11299751-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11326182-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019217513-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434502-B2 |
| priorityDate |
2002-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |