| abstract |
A drug containing, as the active ingredient, an antibody composition produced with the use of cells tolerant to a lectin recognizing a sugar chain structure in which an α-bond is formed between the 6-position of N-acetylglucosamine at the reducing end of an N-glycoside bond-type complex sugar chain and the 1-position of fucose. This drug is appropriate for patients suffering from FcϜRIIIa polymorphism who cannot be treated with a drug containing, as the active ingredient, an antibody composition produced from cells not tolerant to a lectin recognizing a sugar chain structure in which an α-bond is formed between the 6-position of N-acetylglucosamine at the reducing end of an N-glycoside bond-type complex sugar chain and the 1-position of fucose. |