| abstract |
The invention relates to a novel method for coating substrates with calcium phosphate. Prior art methods do not permit temperature-sensitive substrates or particles to be coated with calcium phosphates or it requires several method steps for carrying out this coating. The aim of the novel method is to be able to carry out a simple coating for all materials as well as for particles. To this end, the invention provides that the substrate to be coated is placed in a calcium phosphate gel, whereupon this substrate that is coated with the gel is dried. Afterwards, the calcium phosphate particles not adhering to the substrate are removed. According to the invention, the substrate can also be placed inside a colloidal solution of SiO2 containing a calcium phosphate, whereupon the mixture is constantly set in motion, the solvent is removed, and the substrate is provided with a calcium phosphate layer by condensing the colloidal SiO2 on the surface of the substrate. The coated substrates can, particularly when it concerns coated particles, be used as bone substitute material. |