| abstract |
A pharmaceutical composition for administering a compound represented by the general formula (I) or the like and a compound represented by the general formula (II) either simultaneously or separately at a time interval: (I) (II) wherein X is a benzimidazole ring group; Y1 is oxygen or sulfur; Z is a thiazolidinedione group or the like; R is hydrogen, C1-6 alkyl, or the like; m is an integer of 1 to 5; Ra is bromo or iodo; Rb is hydrogen, halogeno, or the like; Rc is -NRkORl [wherein Rk is hydrogen or the like; and Rl is C3-10 cycloalkyl or the like]; and Rd, Re and Rf are each independently hydrogen, halogeno, or the like. |