| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f6e33603375c486b0ab3505830af9e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b28b4e42d244536fa02337faba31720e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71a82b1d9275a6c8e06623b2e1429856
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cad51e8430ff4a74eefc1b479de322fc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2878
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39541
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate |
2002-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e191c9ae76ee0d3f26a1e6866302e81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f48066658ab6fe24421ba64b9761bfa0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53335e31b92b2ff20f5b6f39ffc9b86d |
| publicationDate |
2003-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-03020768-A1 |
| titleOfInvention |
A method for the treatment or prevention of bone erosion |
| abstract |
There is provided a method for the treatment or prevention of bone erosion caused by a disease that activates osteoclasts (e.g. rheumatoid arthritis) comprising administering to a patient an anti-human Fas monoclonal antibody HFE7A or a humanized version thereof, as well as a composition for use in such a method. There is also provided a method for testing a substance for the treatment or prevention of bone erosion comprising: transplanting pieces of dentine and synovial tissue from a patient suffering from a disease that activates osteoclasts to immunodeficient non-human mammals; administering the substance to be tested to at least one of the test animals and a control to at least one different test animal and breeding them; and then extracting said pieces of dentine from the test animals and counting the number of resorption pits formed on the surface of each piece that was in contact with said sample of synovial tissue. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102170905-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102170905-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03103710-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005016350-A1 |
| priorityDate |
2001-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |