Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_174898adc234db9836cfd6101f95e88f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50de4ade4243357e275c1ca577bded9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39b620363843d772538eca74ae87e8e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce157348afa0b11e07587ab364ea3396 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3cf146bb07bb03727a5ccdcf7927669a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_31f7108b6aa52433b107fdfbddd09b2b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
filingDate |
2002-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c23cbbf4acff53f4e9a5aac2a7033507 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45cd0aed366c6bb8c4626a04387a431e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82da81778bf6a1bd5f606e882cefbfaa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc20a5c946be71b3186c529a14ffbaa2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f376f56b49709425a79100463171caeb |
publicationDate |
2003-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-03010308-A2 |
titleOfInvention |
Control of gene expression |
abstract |
A method of suppressing the expression of a selected endogenous gene in a eukaryotic cell the method comprising introducing into the cell (a) a polypeptide comprising a nucleic acid binding portion which binds to a site at or associated with the selected gene and a modifying portion which comprises a polypeptide or peptidomimetic which is capable of modulating covalent modification of nucleic acid or chromatin, for example a chromatin inactivation portion, or (b) a polynucleotide encoding said polypeptide. The binding of the molecule to nucleic acid may be modulated by a ligand and the molecule may comprise a ligand binding portion. The nucleic acid binding portion may be a nucleic acid binding portion of a nuclear receptor DNA binding protein. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10351867-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014134567-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006043810-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106995820-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004050885-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004050885-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11479781-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106995820-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008517903-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105189760-A |
priorityDate |
2001-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |