| abstract |
An adhesive preparation which comprises a flexible support and formed on one side thereof a pressure-sensitive adhesive layer comprising a drug, an absorption accelerator, and a pressure-sensitive adhesive, wherein (i) the drug is estradiol, (ii) the absorption accelerator comprises a combination of at least either of sorbitan monolaurate and polyethylene glycol monolaurate and at least one member selected among higher fatty acid esters which are liquid at room temperature and hydrocarbons which are liquid at room temperature, and (iii) the pressure-sensitive adhesive is an acrylic one. |