| abstract |
The invention relates to a transdermal therapeutic system embodied as a matrix or reservoir system, characterized in that it contains at least one basic or neutral reacting pharmaceutical active substance; in that it contains one contact adhesive polymer having acrylic acid or methacryilic acid units as part of the chain, wherein the carboxyl group content, in relation to the mean polymeric material, amounts to 0.5 to 10.0 % (w/w) and the carboxyl groups are present with a stoichiometry of 5-100 %, preferably 10-50 %, in the form of an alkali salt or an alkaline earth salt. Water-binding additives can also be contained to reduce moisture sensitivity. |