| abstract |
The present invention provides molecules, designed using the estrogen pharmacophore, that possess predicted and demonstrated estrogenic and/or estrogenic modulatory biological activity. The present invention also provides a method for chemically synthesizing 11β-methoxy-7α-methylestra-1,3,5(10)-triene-3,17β-diol and related molecules. New uses for 11β-methoxy-7α-methylestra-1,3,5(10)-triene-3,17β-diol, for providing estrogenic bioactivity or estrogenic modulatory biological activity, when administered with a pharmaceutically or cosmetically acceptable carrier are also provided. The molecules of the present invention may be used to treat conditions in which estrogenic modulatory bioactivity or modulation of estrogenic biological activity is desired. |