abstract |
The present invention relates to complex compositions of anticancer drugs, which are administrated in combination with antimalarial drugs for reducing a minimum IC50 of anticancer drugs and inhibiting development of drug resistance of cancer cells caused by anticancer drugs, thereby enhancing the effect of the anticancer drugs. More particularly, the present invention relates to complex compositions of anticancer drugs, which are administrated in combination with antimalarial drugs for a minimun IC50 of anticancer drugs and inhibiting development of drug resistance of cancer cells caused by anticancer drugs, thereby enhancing the effect of the anticancer drugs; in which the anticancer drugs are selected from the group consisting of doxorubicin, cisplatin, and the like and the antimalarial drugs are selected from the group consisting of hydroxchloroquine, chloroquine, primaquine and the like. |