| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bc5292a07e34d16eb1d033a16d3aec3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec75e3dbf8eaff09d1173f402063a6bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53f3caaef4a047a39b97e90e828e3920
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_756ecda789378db783db5fef417893d3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96425
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G11B5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2002-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a27362349df446cb5af0e81d0696b9d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc2ec137e69ab59727599078a510c89c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3c7695159e1f1af449a47bde9c58caa |
| publicationDate |
2002-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-02100333-A2 |
| titleOfInvention |
Inhibitors of reggamma |
| abstract |
The invention provides a mutant activator of a 20S proteasome. More specifically, relates to a mutant activator comprising a mutant REGϜ protein that promotes the 20S proteasome to cleave protein or peptide substrates. The invention also provides a methods of screening for compounds that inhibit or enhance REGϜ activated 20S proteosomal cleavage and method of treating subjects with neurodegenerative diseases characterized by an accumulation of abnormal protein or peptide. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7998684-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1857119-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2351585-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8580759-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1857119-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103601796-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111208301-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103601796-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2351585-A4 |
| priorityDate |
2001-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |