| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32958f3f99a98ccaabfc72177827e9c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_210c8d6b16c95d820401cfaae332ec76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2bcaf91101a370a3d64e3190366357f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed23d64b4f73b9424a80def53f3fe400 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-403
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6897
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6837 |
| filingDate |
2002-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26e7e4393c93f47d983629a0da641ffe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5026cec36ea20ccd7424a352061d06a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf2e440b0bd19ad471690fb0e37e0b57 |
| publicationDate |
2002-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-02081739-A2 |
| titleOfInvention |
Non-enzymatic liposome-linked closely spaced array electrodes assay (nel-ela) for detecting and quantifying nucleic acids |
| abstract |
Target nucleic acids or amplicons thereof bound to immobilized capture oligonucleotides by molecular biological reations, are detected and quantified with affinity liposomes containing encapsulated electrochemically detectable reporter molecules susceptible to redox recycling and surface-attached affinity components capable of specifically binding to captured target nucleic acids or amplicons thereof in a structure restricted manner. Specifically bound affinity liposomes are lysed by temperature- or detergent-mediated mechanisms and released reporter molecules are quantitated via redox recycling using voltammetry in conjunction with a closely spaced array of thin film nobel metal electrodes. The quantitiy of released reporter molecules is a proportional measure of the quantity of target nucleic acids in the sample. For amplified assay procedures polymeric carrier molecules capable of binding multiple affinity liposomes or preformed complexes of affinity liposomes are utilized. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11780970-B2
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017114859-A1 |
| priorityDate |
2001-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |