abstract |
The present invention relates to dopamine and serotonin receptor ligands having the general formula (I) wherein one of Y?1 and Y2¿ is N, which is bound to Y4, Y3 is Z-CH¿2?, CH2-Z or CH2CH2 and the further meanings of Y?1, Y2, Y3, Y4¿, Z, W, n, m, X, R?1-R9 and R10¿ are as given in the claims and the description. The compounds of the invention are useful in the treatment of certain psychiatric and neurological disorders, i.e. schizophrenia, other psychoses, anxiety disorders, depression, migraine, cognitive disorders, ADHD and sleep improvement. |