| abstract |
Disclosed herein is a method for making compounds that are useful as caspase inhibitor prodrugs of formula (I), wherein R1 is an optionally substituted group selected from an aliphatic group, aralkyl group, heterocyclylalkyl group or aryl group, and R2 is preferably a P¿2?-P4 moiety of a caspase inhibitor. Key intermediates include the azidolactones (III) and (VIII). |