| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f009fff2f31da9529566f0ef0e9f3b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35eaeda0014dd5ef0a7ca1e90db69877
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a358f9022bbc8907eed2d371939b7d3e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-9121 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 |
| filingDate |
2001-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca7a80d510a8d660d5164e52204a901d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_437e25e44c51316de893ecdbaff30ef7 |
| publicationDate |
2001-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0161031-A2 |
| titleOfInvention |
Improved assay for protein tyrosine phosphatases |
| abstract |
The invention relates in part to screening assays for identifying agents that alter the interaction between a protein tyrosine phosphatase (PTP) and its tyrosine phosphorylated polypeptide substrate, using fluorescence energy signals generated by detectably labeled substrates. Assays are provided in certain embodiments, including high throughput screening assays, wherein candidate agents are screened by fluorescence polarization for their ability to influence (i) binding of substrate trapping mutant PTPs to substrates, or (ii) dephosphorylation of tyrosine phosphorylated substrates by PTPs. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0164939-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0164939-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7157240-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1578961-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1578961-A4 |
| priorityDate |
2000-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |